Risk-Benefits of Oxcarbazepine vs Carbamazepine
نویسندگان
چکیده
منابع مشابه
Crystal polymorphism in a carbamazepine derivative: oxcarbazepine.
Although crystal polymorphism of carbamazepine (CBZ), an anticonvulsant used to treat epilepsy, has been known for decades, the phenomenon has only recently been noted for its keto-derivative oxcarbazepine (OCB). Here it is demonstrated that OCB possesses at least three anhydrous polymorphs. Although all forms are morphologically similar, making differentiation between crystal modifications by ...
متن کاملChange of pitch due to carbamazepine and oxcarbazepine independently
Absolute pitch (AP) is the term used to denote the cognitive ability to spontaneously and effortlessly identify and vocally produce specific musical tones without a reference note. Abnormalities of pitch perception are a recognized rare side effect of carbamazepine (CBZ). The mechanism of this side effect is not clear. The same symptom may also be associated with oxcarbazepine (OXC) although th...
متن کاملRelation of blood platelet count during carbamazepine and oxcarbazepine treatment with daily dose, and serum concentrations of carbamazepine, carbamazepine-10, 11-epoxide, and 10-hydroxycarbazepine.
BACKGROUND Carbamazepine (CBZ) occasionally causes haematological disorders such as thrombocytopenia, and recently a case of oxcarbazepine (OXCBZ)-induced thrombocytopenia has been described. The aim of our study was blood platelet count determination in epileptic patients treated with CBZ and OXCBZ, and its relationship with the dose and serum levels of these drugs and its metabolites. METHO...
متن کاملReproductive effects of valproate, carbamazepine, and oxcarbazepine in men with epilepsy.
BACKGROUND Recent observations have indicated that reproductive endocrine disorders are common among women taking valproate (VPA) for epilepsy, but it is not known whether respective abnormalities develop in men taking VPA for epilepsy. Carbamazepine (CBZ) may induce endocrine disorders in men with epilepsy, but the endocrine effects of oxcarbazepine (OXC) are not known. METHODS Reproductive ...
متن کاملEffects of oxcarbazepine versus carbamazepine on tinnitus: A randomized double-blind placebo-controlled clinical trial
BACKGROUND It is still a challenge to find an effective treatment for tinnitus. The aim of this study was the evaluation of carbamazepine and oxcarbazepine effects on tinnitus. METHODS In a randomized double-blind clinical trial, 57 patients who were visited in a university hospital due to chronic non-pulsatile tinnitus, were randomized in three groups and treated with carbamazepine (300-600 ...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 2004
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-18-10-7